Research Article

Inhibition of eIF2α Dephosphorylation Protects Hepatocytes from Apoptosis by Alleviating ER Stress in Acute Liver Injury

Figure 1

The impact of ER stress on apoptosis. PERK/eIF2α is an important factor in the main pathways for ER stress-mediated apoptosis. eIF2α integrates multiple signals and involves both prosurvival and proapoptotic pathways of ER stress.