Tanshinone IIA Alleviates CCL2-Induced Leaning memory and Cognition Impairment in Rats: A Potential Therapeutic Approach for HIV-Associated Neurocognitive Disorder

Figure 10

The schematic diagram of our hypothesis. Tan IIA can protect CCL2-induced learning memory and cognition impairment, and its mechanism is related to reducing brain tissue inflammation, and antioxidative stress, and finally inhibiting the excessive apoptosis of nerve cells, indicating that Tan IIA has potential nerve protective effects.