Minimum Clinically Important Difference of Gross Motor Function and Gait Endurance in Children with Motor Impairment: A Comparison of Distribution-Based Approaches

Table 3

MCID estimates for all outcome measures for the 5 distribution-based approaches and the survey, divided for ABI and CP etiologies and GMFCS subgroups.

	M_srm		L_srm		ES		SEM		SDB		Survey
	ABI	CP	ABI	CP	ABI	CP	ABI	CP	ABI	CP	ABI	CP
6minWT (m)
I-II	20	4	32	6	26	25	32	28	36	17	30	25
III	29	9	46	14	23	16	28	11	37	19	20	20
IV	24	17	38	27	30	15	37	10	46	23	15	14
Overall	20	6	32	10	29	23	35	17	38	19	—	—
GMFM-88 (%)
I-II	1.6	0.1	2.5	0.1	3.4	1.7	1.7	1.0	3.8	1.0	5.0	4.0
III	1.5	0.1	2.3	0.2	4.6	2.2	2.3	1.1	4.0	1.3	5.7	4.0
IV	0.9	0.1	1.5	0.1	5.6	2.1	2.8	2.5	3.8	1.2	3.0	3.0
Overall	1.1	0.1	1.8	0.1	5.3	3.0	2.7	1.5	3.8	1.2	—	—
DIM D (%)
I-II	2.9	0.8	4.6	1.2	4.7	3.3	2.4	1.7	5.9	2.6	5.0	4.0
III	1.9	0.6	3.0	1.0	5.8	4.1	2.9	2.0	5.2	2.5	4.0	4.0
IV	3.0	2.1	4.8	3.4	5.9	3.3	3.0	1.6	7.1	4.6	5.1	5.0
Overall	2.3	0.8	3.6	1.2	6.5	5.2	3.2	2.6	6.1	3.2	—	—
DIM E (%)
I-II	4.3	0.2	6.8	0.3	5.6	4.5	2.8	2.3	7.6	1.5	5.0	4.0
III	2.8	0.6	4.5	1.0	5.3	3.4	2.7	1.7	6.1	2.4	4.0	4.0
IV	1.5	0.1	2.4	0.2	4.8	2.5	2.4	1.2	4.8	1.0	4.2	3.0
Overall	2.8	0.3	4.4	0.4	6.0	4.9	3.0	2.5	6.5	1.9	—	—