Evaluation of the Diagnostic Efficacy of Xpert CT/NG for Chlamydia trachomatis and Neisseria gonorrhoeae

Table 1

Characteristics about CT from included articles.

Author	Year	Country	Study design	Gold standard	Source of specimens	Bacterial species	Type of specimens	Result
								TP	FP	FN	TN
Goldenberg	2012	Britain	Prospective	PCR	409 self-collected specimen	CT	Anorectal	37	3	6	363
Gaydos	2013	America	Prospective	PCR	1710 clinical specimens	CT	Endocervical	76	7	2	1625
					1718 clinical specimens		Urine^a	80	3	2	1633
					1386 clinical specimens		Urine^b	79	1	2	1304
Jenson	2013	East Africa	Prospective	PCR	144 specimens from trachoma-endemic community	CT	Ocular	35	5	0	87
Causer	2015	Australia	PCR	PCR	198 clinical specimens	CT	Urine	16	1	0	181
Peuchan	2015	France	Prospective	PCR	377 clinical specimens	CT	Vaginal	37	0	1	339
Geiger	2016	America	Prospective	PCR	285 self-collected specimens	CT	Ocular	1	0	1	142
							Anorectal	15	0	2	124
Bristow	2017	America	Prospective	PCR	393 clinical specimens	CT	Anorectal	42	2	7	342
Cosentino	2017	America	Prospective	PCR	399 clinical specimens	CT	Anorectal	51	6	3	339
					394 clinical specimens		Pharyngeal	8	2	0	384
					224 clinical specimens		Urine^b	9	0	1	214
					170 clinical specimens		Vaginal	10	0	1	152
Dize	2017	America	Prospective	PCR	448 self-collected specimens	CT	Anorectal	21	1	1	378
Wilson	2017	America	Prospective	PCR	50 clinical specimens	CT	Urine^b	8	1	2	39
					1112 clinical specimens		Urine^a	101	8	24	979
Causer	2018	Australia	Prospective	PCR	2486 self-collected specimens	CT	Urine, vaginal	209	11	3	2263
Badman	2018	Australia	Prospective	PCR	326 self-collected specimens	CT	Anorectal^c	144	8	5	169
							Anorectal^d	116	3	4	127
							Anorectal^e	28	5	1	42
Gaydos	2018	America	Prospective	PCR	127 clinical specimens	CT	Endocervical	10	0	0	117
Garrett	2019	South Africa	Prospective	PCR	247 clinical specimens	CT	Vaginal	37	5	0	205

^aThese specimens were collected from female. ^bThese specimens were collected from male. ^cThese specimens were collected from “men who have sex with men,” “transgender women,” and “female sex workers.” ^dThese specimens were collected from “female sex workers.” ^eThese specimens were collected from “men who have sex with men” and “transgender women.” TP: true positive; FP: false positive; FN: false negative; TN: true negative.