Evaluation of the Diagnostic Efficacy of Xpert CT/NG for Chlamydia trachomatis and Neisseria gonorrhoeae

Table 2

Characteristics about NG from included articles.

Author	Year	Country	Study design	Gold standard	Source of specimens	Bacterial species	Type of specimens	Result
								TP	FP	FN	TN
Goldenberg	2012	Britain	Prospective	PCR	409 self-collected specimens	NG	Anorectal	51	0	5	353
Gaydos	2013	America	Prospective	PCR	1710 clinical specimens	NG	Endocervical	22	0	0	1688
					1718 clinical specimens		Urine^a	22	1	1	1694
					1386 clinical specimens		Urine^b	49	1	1	1335
Causer	2015	Australia	Prospective	PCR	198 clinical specimens	NG	Urine	7	0	0	191
Peuchan	2015	France	Prospective	PCR	377 clinical specimens	NG	Vaginal	7	0	0	370
Geiger	2016	America	Prospective	PCR	285 self-collected specimens	NG	Ocular	7	0	2	135
							Anorectal	4	0	0	137
Bristow	2017	America	Prospective	PCR	391 clinical specimens	NG	Anorectal	38	2	5	346
					448 clinical specimens		Pharyngeal	31	4	3	410
Cosentino	2017	America	Prospective	PCR	399 clinical specimens	NG	Anorectal	28	2	0	369
					394 clinical specimens		Pharyngeal	36	9	1	348
					224 clinical specimens		Urine^b	12	0	0	212
					170 clinical specimens		Vaginal	4	0	1	165
Dize	2017	America	Prospective	PCR	448 self-collected specimens	NG	Anorectal	7	0	0	394
Wilson	2017	America	Prospective	PCR	50 clinical specimens	NG	Urine^b	4	0	0	46
					1112 clinical specimens		Urine^a	41	5	7	1059
Causer	2018	Australia	Prospective	PCR	2486 self-collected specimens	NG	Urine, vaginal	145	2	0	2339
Badman	2018	Australia	Prospective	PCR	326 self-collected specimens	NG	Anorectal^c	93	0	7	226
							Anorectal^d	72	0	6	172
							Anorectal^e	22	0	0	54
Gaydos	2018	America	Prospective	PCR	127 clinical specimens	NG	Endocervical	5	0	0	122
Garrett	2019	South Africa	Prospective	PCR	247 clinical specimens	NG	Vaginal	12	0	0	235

^aThese specimens were collected from female. ^bThese specimens were collected from male. ^cThese specimens were collected from “men who have sex with men,” “transgender women,” and “female sex workers.” ^dThese specimens were collected from “female sex workers.” ^eThese specimens were collected from “men who have sex with men” and “transgender women.” TP: true positive; FP: false positive; FN: false negative; TN: true negative.