Research Article

Ultrashort Wave Combined with Human Umbilical Cord Mesenchymal Stem Cell (HUC-MSC) Transplantation Inhibits NLRP3 Inflammasome and Improves Spinal Cord Injury via MK2/TTP Signalling Pathway

Figure 2

Combination therapy suppresses inflammatory responses and improves inflammatory microenvironment in SCI rats. Polarisation markers (iNOS and arg-1) of M1/M2 microglial polarisation states detected with IF represented in iNOS/IBA-1 (a) and arg-1/IBA-1 (b) costaining (). (c) Contents of inflammatory factors (M-CSF, IL-6, and IL-10) determined using ELISA. “, #, &” indicated significant difference (),” vs. Sham group, “#” vs. SCI group, and “&” vs. rats treated with monotherapy (USW/HUC-MSCs).
(a)
(b)
(c)