Mesenteric Lymph Duct Drainage Attenuates Lung Inflammatory Injury and Inhibits Endothelial Cell Apoptosis in Septic Rats

Figure 2

Morphologic changes of intestinal mucosa and evaluation of gut injury with Chiu’s scores under light microscopy (magnification, ×200). The control group (a) and the sham operation group (b) had normal villi and glands. By contrast, severe edemas of mucosal villi accompanied with severe intestinal gland injury were observed in the sepsis group. In addition, a large number of intestinal villi disintegrated, the gap of epithelial cells increased, and severe hemorrhage was present, indicative of severe mucosal damage in the sepsis group (c). The putrescence and desquamation of epithelial cells in the intestinal mucosa were attenuated, but mucosal sloughing could be seen at villi tips, and the gap between epithelial cells increased slightly in the sepsis+MLD group (d). The data of Chiu’s scores were expressed as , (e). Results were compared by one-way ANOVA with Student-Newman-Keul’s posthoc test. vs. control group.

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(b)

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(e)