Research Article

Multimodal α-Glucosidase and α-Amylase Inhibition and Antioxidant Effect of the Aqueous and Methanol Extracts from the Trunk Bark of Ceiba pentandra

Table 1

Summary of the antioxidant and carbohydrate digestive enzyme inhibitory effects of C. pentandra extracts.

Antioxidant activitiesCarbohydrate digestive enzymes
Superoxide anionHydrogen peroxideAAPH proteinH2O2 proteinα-Amylaseα-Glucosidase

Methanol extract51.811.344.841.539.261.09120.60.446.1514.9376.611.14
Aqueous extract34.261.261.7812.0797.950.28140.40.0454.521.6286.490.78
Gallic acid55.661.4390.170.6429.91.74
Ascorbic acid13.844.77
Acarbose20.974.038.4911.76
2.776.1333.6574.2364.54270.40
0.03840.0058<0.0001<0.0001<0.0001<0.0001

: concentration of the tested substance able to inhibit 50% of the activity; EI: efficiency index, calculated as maximal activity/. The statistical analysis was performed with nonlinear regression and the best fit parameters ( and top) were compared.