Mechanism of Antibacterial Activity of Bacillus amyloliquefaciens C-1 Lipopeptide toward Anaerobic Clostridium difficile

Table 3

Identification of gene clusters potentially involved in the synthesis of secondary metabolites by B. amyloliquefaciens C-1.

Cluster^a	Type^b	From^c	To^c	Secondary metabolite^d
1	Saccharide	165858	190731	Unknown
2	NRPS	556597	622004	Surfactin
3	Fatty acid	785309	810347	Unknown
4	NRPS	938299	967890	Iturins
5	Other KS	1158436	1199680	Butirosin
6	Fatty acid	1227747	1248724	Unknown
7	Terpene	1281720	1302460	Unknown
8	Fatty acid	1314519	1339344	Citrulline
9	Putative	1378928	1396630	Molybdenum cofactor
10	Lantipeptide	1406687	1451837	Unknown
11	Transatpks	1624433	1706630	Macrolactin
12	Transatpks-NRPS	1932737	2035409	Bacillaene
13	Transatpks-NRPS	2100037	2237835	Fengycin
14	Terpene	2263057	2284940	Unknown
15	T3PKS	2348257	2389357	Unknown
16	Transatpks	2504342	2604794	Difficidin
17	Bacteriocin-NRPS	3235204	3301995	Bacillibactin
18	Saccharide	3504667	3530078	Unknown
19	Saccharide	3624018	3678829	Teichuronic
20	Saccharide	3823278	3895655	Bacilysin

^aClusters identified using default settings of antiSMASH 5.0. ^bClass of gene cluster according to antiSMASH 5.0. ^cLocation of gene clusters in the B. amyloliquefaciens C-1 genome. ^dSecondary metabolites potentially produced based on the gene clusters.