Prevalence and Risk Factors of Cytopenia in HIV-Infected Patients before and after the Initiation of HAART

Table 2

The risk factors of cytopenia in HAART-naïve patients.

	df	Univariate analysis OR (95% CI)	value	Multivariate analysis AOR (95% CI)	value
Age (years)	1
<40		Ref	—	Ref	—
≥40		1.5 (1.21, 1.9)	<0.01	1.51 (1.21, 1.9)	<0.01
Sex	1
Male		Ref	—	Ref	—
Female		2.9 (2, 4.3)	<0.001	2.92 (2, 4.28)	<0.001
WHO stage	3		<0.001		<0.001
I		Ref	—	Ref	—
II		0.73 (0.44, 1.22)	0.064	0.73 (0.44, 1.22)	0.23
III		1.03 (0.67, 1.59)	0.65	1.03 (0.67, 1.59)	0.9
IV		1.94 (1.45, 2.58)	<0.001	1.94 (1.45, 2.57)	<0.001
HCV-coinfection	1
No		Ref	—	Ref	—
Yes		1.8 (1.18, 2.76)	0.015	1.8 (1.12, 2.87)	0.007
CD4 (cells/μl)	1
≥200		Ref	—	Ref	—
<200		3.57 (2.8, 4.5)	<0.001	3.57 (2.83, 4.5)	<0.001
HIV RNA	1
<100000		Ref	—	Ref	—
≥100000		1.55 (1.24, 2.58)	<0.001	1.55 (1.24, 1.92)	<0.001
BMI	2		0.034		0.034
18.5–24		Ref	—	Ref	—
<18.5		1.6 (1.12, 2.31)	0.01	1.61 (1.1, 2.32)	0.01
>24		1.2 (0.9, 1.54)	0.23	1.18 (0.9, 1.54)	0.23
Infection routes	1
Others		Ref	—
Sexual		1.27 (0.6, 2.65)	0.53
HCV-coinfection	1
No		Ref	—
Yes		1.94 (0.98, 3.82)	0.056

Note: df, degree of freedom; WHO, World Health Organization; BMI, body mass index; Ref, reference.