Research Article
An Artificial Intelligence Model for Predicting 1-Year Survival of Bone Metastases in Non-Small-Cell Lung Cancer Patients Based on XGBoost Algorithm
Table 1
Demographic and clinicopathologic features of 5973 NSCLC patients with BM in the SEER database.
| | Variables | Training set | Validation set | | |
| | Age () | | | 0.336 | 0.737 | | Size () | | | 0.423 | 0.673 | | Race | | | 1.191 | 0.551 | | Black | 519 (12.4%) | 221 (12.3%) | | | | Other | 392 (9.4%) | 184 (10.3%) | | | | White | 3272 (78.2%) | 1385 (77.4%) | | | | Sex | | | 0.146 | 0.702 | | Female | 1789 (42.8%) | 756 (42.2%) | | | | Male | 2394 (57.2%) | 1034 (57.8%) | | | | Primary site | | | 0.350 | 0.950 | | Main bronchus | 173 (4.1%) | 79 (4.4%) | | | | Overlapping lesion of lung | 31 (0.7%) | 12 (0.7%) | | | | Lung, NOS | 182 (4.4%) | 76 (4.2%) | | | | Lobe | 3797 (90.8%) | 1623 (90.7%) | | | | Histologic type | | | 6.010 | 0.050 | | ADC | 2688 (64.3%) | 1163 (65.0%) | | | | Others | 558 (13.3%) | 269 (15.0%) | | | | SCC | 937 (22.4%) | 358 (20.0%) | | | | Grade | | | 2.367 | 0.500 | | I | 217 (5.2%) | 86 (4.8%) | | | | II | 1259 (30.1%) | 536 (29.9%) | | | | III | 2596 (62.1%) | 1131 (63.2%) | | | | IV | 111 (2.7%) | 37 (2.1%) | | | | Laterality | | | 0.277 | 0.599 | | Left—origin of primary | 1750 (41.8%) | 762 (42.6%) | | | | Right—origin of primary | 2433 (58.2%) | 1028 (57.4%) | | | | T stage | | | 5.837 | 0.120 | | T1 | 446 (10.7%) | 184 (10.3%) | | | | T2 | 1168 (27.9%) | 555 (31.0%) | | | | T3 | 1139 (27.2%) | 469 (26.2%) | | | | T4 | 1430 (34.2%) | 582 (32.5%) | | | | N stage | | | 3.715 | 0.294 | | N0 | 887 (21.2%) | 343 (19.2%) | | | | N1 | 373 (8.9%) | 170 (9.5%) | | | | N2 | 2039 (48.7%) | 902 (50.4%) | | | | N3 | 884 (21.1%) | 375 (20.9%) | | | | M stage | | | 0.916 | 0.339 | | M1a | 110 (2.6%) | 55 (3.1%) | | | | M1b | 4073 (97.4%) | 1735 (96.9%) | | | | Radiotherapy | | | 1.270 | 0.260 | | No | 1734 (41.5%) | 714 (39.9%) | | | | Yes | 2449 (58.5%) | 1076 (60.1%) | | | | Chemotherapy | | | 0.099 | 0.753 | | No | 1490 (35.6%) | 630 (35.2%) | | | | Yes | 2693 (64.4%) | 1160 (64.8%) | | | | Surgery | | | 1.452 | 0.228 | | No | 4013 (95.9%) | 1729 (96.6%) | | | | Yes | 170 (4.1%) | 61 (3.4%) | | | | Brain metastasis | | | 2.261 | 0.133 | | No | 3239 (77.4%) | 1354 (75.6%) | | | | Yes | 944 (22.6%) | 436 (24.4%) | | | | Liver metastasis | | | 0.002 | 0.960 | | No | 3330 (79.6%) | 1426 (79.7%) | | | | Yes | 853 (20.4%) | 364 (20.3%) | | | | Lung metastasis | | | 0.576 | 0.448 | | No | 2999 (71.7%) | 1266 (70.7%) | | | | Yes | 1184 (28.3%) | 524 (29.3%) | | | | Insurance status | | | 1.036 | 0.309 | | Insured | 4059 (97.0%) | 1728 (96.5%) | | | | Uninsured | 124 (3.0%) | 62 (3.5%) | | | | Marital status | | | 0.099 | 0.753 | | Married | 2412 (57.7%) | 1040 (58.1%) | | | | Unmarried | 1771 (42.3%) | 750 (41.9%) | | |
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NSCLC: non-small-cell lung cancer; BM: bone metastasis; ADC: adenocarcinoma; SCC: squamous cell carcinoma.
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