Systematic Investigation of Polyurethane Biomaterial Surface Roughness on Human Immune Responses <i>in vitro</i>

<div>Pro-inflammatory and anti-inflammatory cytokine production from PBMCs cultured on polyurethane with different surface roughness. PBMCs were cultured for three days on polyurethane of increasing surface roughness (P0–P7), after which the concentrations of pro-inflammatory (a) and anti-inflammatory (b) cytokines were assessed using multiplexed bead-based sandwich immunoassays. For IL-10, the samples TCP, P0 and P2 were below the lower limit of quantification (3 pg/mL) and therefore do not contain error bars. 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TCP, tissue culture polystyrene.</div>

BioMed Research International

fig8

Figure 8

Figure 8: Systematic Investigation of Polyurethane Biomaterial Surface Roughness on Human Immune Responses <i>in vitro</i> 

BioMed Research International

Systematic Investigation of Polyurethane Biomaterial Surface Roughness on Human Immune Responses in vitro

Figure 8