Research Article
[Retracted] High-Fat Diet Promotes DSS-Induced Ulcerative Colitis by Downregulated FXR Expression through the TGFB Pathway
Figure 1
High-fat diet aggravates UC progression in a DSS-induced mouse model: (a) body weight change in mice on the treatment with DSS and HFD for 2 weeks; (b) DAI score change in mouse treatment with DSS and HFD for 2 weeks; (c) total bile acid concentration of serum in three experiment groups, respectively; (d) total RNA was extracted from the control group, DSS group, and DSS combination with HFD-treated colon to investigate the mRNA expression level of FXRα, Shp, and lbabp which were the target genes of FXR. , , and and for each group.
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