Review Article
Clinical Significance of PIK3CA Gene in Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis
Table 4
Meta-analyses for the association of PIK3CA with survival of non-small-cell lung cancer patients.
| | Analysis | No. of studies | HR (95% CI) | Log-rank value | (%) | value |
| | Mutation | | | | | | | Overall survival | 8 | 1.55 (1.13-2.13) | 0.007 | 18.0 | 0.288 | | Progression-free survival | 7 | 1.48 (1.06-2.08) | 0.023 | 0.0 | 0.739 | | Cancer-specific survival | 1 | 2.63 (1.00-6.92) | 0.05 | — | — | | Expression | | | | | | | Overall survival | 3 | 0.80 (0.58-1.12) | 0.193 | 19.8 | 0.287 |
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HR: hazard ratio; CI: confidence interval.
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