Research Article
Association of Leptin Gene Polymorphisms with Rheumatoid Arthritis in a Chinese Population
Table 4
Haplotype analysis of SNPs in leptin gene in RA patients and controls.
| | Haplotype | Case [ (%)] | Control [ (%)] | | value | OR (95% CI) |
| | rs2167270-rs10244329-rs2071045 | | AAC | 2.41 (0.002) | 1.50 (0.001) | — | — | — | | AAT | 1.77 (0.001) | 0.59 (0.000) | — | — | — | | ATC | 5.19 (0.004) | 7.48 (0.006) | — | — | — | | ATT | 243.63 (0.205) | 248.44 (0.207) | 0.030 | 0.862 | 0.983(0.806-1.198) | | GAC | 666.07 (0.560) | 671.51 (0.561) | 0.005 | 0.944 | 0.994 (0.845-1.170) | | GAT | 221.75 (0.186) | 219.41 (0.183) | 0.036 | 0.850 | 1.020 (0.829-1.255) | | GTC | 3.33 (0.003) | 4.52 (0.004) | — | — | — | | GTT | 45.85 (0.039) | 44.56 (0.037) | 0.028 | 0.868 | 1.036 (0.681-1.578) |
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CI: confidence interval; OR: odds ratios; : number. |
