Gut Microbiota-Bile Acid Crosstalk in Diarrhea-Irritable Bowel Syndrome

Table 1

Summary of the alterations of the gut microbiota relating to the bile acid metabolism in IBS.

Bacteria	Reactions	Percentage in IBS	Citations
Lactobacillus	Deconjugation	Lower	[35, 164–167]
Bifidobacterium		Lower	[164, 166, 168–171]
Listeria		—	[9, 172]
B. vulgatus		—	[172–174]
Bacteroides		Higher	[9, 16, 20, 47]
Clostridium		Higher	[9, 16, 47]
Enterococcus		Higher	[22, 34]
Clostridium	7α-Dehydroxylation	Higher	[10, 12–14]
Eubacterium		lower	[9, 34, 175]
Peptostreptococcus	Oxidation and epimerization	—	[47, 172]
Escherichia		Higher	[35, 172]
Bacteroides		Higher	[20, 176]
Clostridium		Higher	[16, 42, 49, 172, 177]
Eubacterium		lower	[34, 175]
Eggerthella		—	[172]
Ruminococcus		Higher	[172, 178, 179]
Bifidobacterium		lower	[47, 178]
Lactobacillus		Lower	[35, 47, 164, 165–167]
Clostridium	Desulfation	Higher	[47, 180, 181]
Peptococcus		Higher	[22, 47, 182]
Fusobacterium		Lower	[47, 175, 183]
Proteobacteria		Higher	[184, 185]
Pseudomonas		—	[172]
Bacteroides	Esterification	Higher	[34, 176]
Methanogens	Others	Lower	[186, 187]
Veillonella		Higher	[5, 178, 184]
Faecalibacterium		Lower	[5, 184]
Lachnospiraceae		Higher	[184]
Actinobacteria		Lower	[184, 185]
Enterobacter		Higher	[35]
Erysipelotrichaceae		Lower	[178]

Abbreviations: IBS: irritable bowel syndrome.