Noninvasive Prediction of TERT Promoter Mutations in High-Grade Glioma by Radiomics Analysis Based on Multiparameter MRI

Table 2

Results of dimensionality reduction and the ICC for each feature.

Abbreviation	VOI	Image type	Feature class	Feature name	ICC
					Intra-	Inter-
t1c_necrosis_glszm_6	Necrosis	T1c_original	glszm	GrayLevelNonUniformity	0.977	0.951
t1c_necrosis_wavelet_448	Necrosis	T1c_wavelet_HLH	glszm	SizeZoneNonUniformityNormalized	0.887	0.856
t2f_necrosis_wavelet_169	Necrosis	T2f_wavelet_LHL	glszm	SizeZoneNonUniformityNormalized	0.908	0.889
necrosis_shap_6	Necrosis	Original	Shape	LeastAxisLength	0.922	0.901
t1c_enhanced_wavelet_217	Enhanced	T1c_wavelet_LHH	glcm	MCC	0.949	0.938
t2f_necrosis_wavelet_660	Necrosis	T2f_wavelet_LLL	gldm	LargeDependenceEmphasis	0.979	0.952

T1c: contrast-enhanced T1-weighted; T2f: T2-weighted flair; VOI: the volume of interest; ICC: intraclass correlation coefficient; Intra-: intra-observer agreement; Inter-: inter-observer agreement.