Research Article

The Association of Stage 1 Hypertension Defined by the 2017 ACC/AHA Guideline with Stroke and Its Subtypes among Elderly Chinese

Table 2

Cox proportional hazards models and the PARs (%) for stroke and subtypes. (N = 7,503).

SBP/DBP categories (mm Hg)StrokeIschemic strokeHemorrhagic stroke
HR (95% CI) valuePAR (95% CI), %HR (95% CI) valuePAR (95% CI), %HR (95% CI) valuePAR (95% CI), %

Model 1a
 <120/<801.00 (ref)1.00 (ref)1.00 (ref)
 120–129/<801.05 (0.74–1.49)0.7791.28 (−7.00–11.05)1.26 (0.82–1.94)0.2876.28 (−4.79–19.35)0.78 (0.42–1.46)0.440−6.00 (−17.73–10.68)
 130–139/80–891.54 (1.17–2.01)0.00212.00 (4.22–20.40)1.76 (1.25–2.47)0.00116.23 (5.94–27.39)1.26 (0.80–1.99)0.3156.36 (−5.42–20.40)
 ≥140/≥902.43 (1.90–3.12)<0.00126.62 (18.54–34.90)2.74 (1.99–3.76)<0.00130.81 (20.26–41.46)2.18 (1.44–3.29)<0.00123.32 (10.27–37.13)

Model 2b
 <120/<801.00 (ref)1.00 (ref)1.00 (ref)
 120–129/<801.03 (0.73–1.46)0.8590.80 (−7.41–10.50)1.23 (0.80–1.88)0.3495.51 (−5.41–18.46)0.77 (0.41–1.43)0.403−6.46 (−18.06–10.06)
 130–139/80–891.47 (1.12–1.92)0.00510.65 (3.02–18.98)1.67 (1.18–2.34)0.00414.58 (4.46–25.65)1.20 (0.76–1.90)0.4314.94 (−6.58–18.78)
 ≥140/≥902.30 (1.79–2.95)<0.00124.74 (16.72–33.02)2.60 (1.89–3.57)<0.00129.09 (18.58–39.77)1.99 (1.32–3.01)0.00120.40 (7.61–34.18)

Model 3c
 <120/<801.00 (ref)1.00 (ref)1.00 (ref)
 120–129/<801.03 (0.72–1.46)0.8850.65 (−7.52–10.34)1.22 (0.80–1.88)0.3575.41 (−5.50–18.37)0.75 (0.40–1.41)0.377−6.82 (−18.27–9.62)
 130–139/80–891.45 (1.11–1.90)0.00710.22 (2.64–18.56)1.65 (1.17–2.33)0.00414.34 (4.23–25.41)1.17 (0.74–1.85)0.5004.23 (−7.17–17.99)
 ≥140/≥902.04 (1.59–2.63)<0.00120.88 (12.91–29.23)2.35 (1.70–3.25)<0.00125.76 (15.27–36.62)1.71 (1.12–2.60)0.01315.43 (2.96–29.30)

CI = confidence interval, DBP = diastolic blood pressure, HR = hazard ratios, PAR = population attributable risk, SBP = systolic blood pressure. aModel 1: unadjusted. bModel 2: adjusted for age, sex, ethnicity, and education. cModel 3: adjusted for age, sex, ethnicity, education, body mass index, smoking, drinking, antihypertension treatment, physical activity, history of diabetes and hyperlipidemia, and family history of hypertension.