Research Article
The Establishment of Esophageal Precancerous Lesion Model by Using p53 Conditional Knockout Mouse in Esophageal Epithelium
Figure 5
NMBA significantly enhanced the ability of p53-knockdown SHEE cells to proliferate. (a) Interference effect of siRNA on the p53 protein expression level in SHEE cells. Scramble siRNA as a negative control is a noninterfering messy oligonucleotide. (b) Soft agar colony-formation assays show that NMBA treatment increased anchorage-independent growths of p53-knockdown immortalized esophageal epithelial cells ( means , means ).
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