Elevated Interleukin-6 Levels within 72 Hours Post Admission Are Associated with Disease Progression in Nonseptic Critically Ill Children

Table 2

Comparison of concentrations of cytokines in serum from nonseptic critically ill children in PICU with or without clinical recovery by day 4.

Cytokines (pg/mL)	Clinical symptoms relieved at day 4		value
	Yes ()	No ()
IL-2	6.39 (3.98-9.29)	4.75 (3.40-9.34)	0.5356
IL-4	3.54 (1.66-13.20)	5.31 (1.75-15.16)	0.5022
IL-6	22.26 (5.61-46.19)	40.65 (12.66-137.50)	0.0474
IL-10	6.04 (4.81-20.77)	10.25 (6.28-28.08)	0.1369
IL-17A	16.91 (7.73-30.30)	21.31 (13.95-42.83)	0.1777
IFN-γ	3.92 (3.28-6.08)	4.90 (3.56-9.52)	0.1428
TNF-α	3.25 (2.47-4.42)	3.12 (2.40-6.42)	0.8496
TNF-β	6.21 (4.02-8.19)	4.95 (3.85-16.34)	0.8744
G-CSF	29.47 (18.11-49.08)	44.10 (19.10-106.00)	0.1321
GM-CSF	6.32 (5.21-10.29)	6.14 (3.99-10.62)	0.7234