Research Article
CCNB2, TOP2A, and ASPM Reflect the Prognosis of Hepatocellular Carcinoma, as Determined by Weighted Gene Coexpression Network Analysis
Table 1
Associations between CCNB2, TOP2A, and ASPM expressions and clinicopathological features.
| Variables | CCNB2 | TOP2A | ASPM | Low () | High () | | P | Low () | High () | | | Low () | High () | | |
| Age (years) | <50 | 29 | 39 | 1.41 | 0.24 | 30 | 38 | 0.84 | 0.36 | 31 | 37 | 0.42 | 0.52 | ≥50 | 152 | 143 | 151 | 144 | 150 | 145 |
| Gender | Female | 51 | 67 | 2.70 | 0.10 | 50 | 68 | 3.49 | 0.06 | 54 | 64 | 0.95 | 0.33 | Male | 130 | 115 | 131 | 114 | 127 | 118 |
| Race | Asian | 65 | 90 | 6.26 | 0.01 | 63 | 92 | 8.56 | 0.003 | 66 | 89 | 5.24 | 0.02 | Non-Asian | 116 | 92 | 118 | 90 | 115 | 93 |
| New tumor events | No | 108 | 91 | 3.05 | 0.08 | 104 | 95 | 0.81 | 0.37 | 110 | 89 | 4.70 | 0.03 | Yes | 73 | 91 | 77 | 87 | 71 | 93 |
| Tumor stage | I-II | 149 | 129 | 6.00 | 0.01 | 147 | 131 | 3.82 | 0.05 | 146 | 132 | 2.91 | 0.09 | III-IV | 32 | 53 | 34 | 51 | 35 | 50 |
| Fetoprotein (ng/ml) | <500 | 125 | 91 | 17.07 | <0.001 | 121 | 95 | 10.19 | 0.001 | 119 | 97 | 9.39 | 0.002 | ≥500 | 16 | 44 | 19 | 41 | 19 | 41 |
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