Research Article

Alterations of the Bile Microbiome in Recurrent Common Bile Duct Stone

Table 1

Baseline characteristics of patients in the recurrence group and the control group.

CharacteristicRecurrence groupControl group value

Patients, 2719NA
Male, (%)17 (63%)11 (57.9%)0.767
Age (years)62 (34-90)53 (14-78)0.010
BMI (kg/m2)24.6 (18.9-33.7)23.4 (19.1-32.3)0.065
TBIL (μmol/L)34.1 (9.2-183.6)24.1 (11.9-443.2)0.260
AST (U/L)33.2 (10.2-388.7)28.1 (15.3-295.7)0.538
ALT (U/L)71.5 (5.3-641.1)74.7 (11.2-308.6)0.378
ALP (U/L)157.1 (46.5-881.9)81.4 (50.2-896.5)0.631
GGT (U/L)168.6 (14.7-1054.2)41.9 (13.8-791)0.259
WBC (109/L)7.7 (1.6-24.8)5.7 (2.8-10.2)0.199
Previous ERCP, (%)17 (74.1%)2 (10.5%)0.001
Previous EST, (%)120<0.001
Previous cholecystectomy, (%)22 (81.5%)2 (10.5%)<0.001
Previous bile duct surgery, (%)13 (48.1%)0<0.001
Mean recurrence time (year)2 (0.5-20)NANA

BMI: body mass index; TBIL: total bilirubin; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase; GGT: gamma-glutamyl transpeptidase; WBC: white blood cell; ERCP: endoscopic retrograde cholangiopancreatography; EST: endoscopic sphincterotomy; NA: not available.