A Phenotypic Characterization of Two Isolates of a Multidrug-Resistant Outbreak Strain of Mycobacterium tuberculosis with Opposite Epidemiological Fitness
Table 1
Most differentially accumulated proteins between Mp and 410 strains.
Protein
Rv number
Log 2 fold changea
value
Description
Rv3221c
Rv3221c
-2.78
8.20-03
Biotinylated protein
IdsA2
Rv2173
-2.57
1.20-03
Probable geranylgeranyl pyrophosphate synthetase
Rv0569
Rv0569
-2.55
1.90-03
Uncharacterized protein
hspX
Rv2031c
-2.52
1.20-09
alpha-Crystallin
fdxA
Rv2007c
-2.27
3.40-04
Ferredoxin
Eis
Rv2416c
-2.19
6.70-03
N-acetyltransferase Eis
Rv2081c
Rv2081c
-2.16
1.20-02
Uncharacterized protein
Rne
Rv2444c
-2.06
3.90-03
Possible ribonuclease E
RpmB2
Rv2058c
2.03
2.40-03
50S ribosomal protein
FtsW
Rv2154c
2.07
1.00-02
Probable peptidoglycan glycosyltransferase
EccDE
Rv0290
2.22
5.90-03
ESX-3 secretion system protein
RpmG1
Rv2057c
2.77
5.10-03
50S ribosomal protein
aLog 2 fold change in the protein relative abundance of the strain M with respect to the strain 410. Negative fold-change values indicate that proteins are overrepresented in the strain 410.
