An Integrated Bioinformatic Analysis of the S100 Gene Family for the Prognosis of Colorectal Cancer

Table 1

The changes in the expression of the S100 family genes at the transcription level between different types of colorectal cancer and colon tissues (Oncomine database).

	Types of colorectal cancer vs. normal colon	Fold change	value	-test	Ref
S100A1	Rectal adenocarcinoma vs. normal	1.009	0.457	0.111	Kaiser Colon [25]
	Colon adenocarcinoma vs. normal	1.003	0.484	0.043	Kaiser Colon [25]
	Colorectal adenocarcinoma vs. normal	1.042	0.143	1.077	Skrzypczak Colorectal [27]
S100A2	Colorectal carcinoma vs. Normal	5.846	2.66E-13	9.915	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	2.591	4.94E-07	7.205	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	9.983	5.77E-46	24.76	Gaedcke Colorectal [26]
S100A3	Colorectal carcinoma vs. normal	1.6	1.82E-08	6.425	Skrzypczak Colorectal [27]
	Rectal adenocarcinoma vs. normal	2.803	4.20E-24	14.11	Gaedcke Colorectal [26]
S100A4	Colorectal carcinoma vs. normal	1.73	1.18E-04	3.923	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	1.292	8.00E-02	1.52	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	1.391	1.00E-01	1.365	Kaiser Colon [25]
S100A5	Colorectal carcinoma vs. normal	1.066	7.00E-02	1.498	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	1.09	2.70E-02	2.212	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	1.057	1.57E-01	1.055	Kaiser Colon [25]
S100A6	Colon adenocarcinoma vs. normal	2.037	6.88E-04	4.931	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	2.735	5.54E-04	4.409	Kaiser Colon [25]
S100A7	Colorectal carcinoma vs. normal	1.411	6.00E-03	2.637	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	1.293	3.52E-04	3.777	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	1.27	5.00E-03	3.11	Kaiser Colon [25]
S100A7A	Colon adenocarcinoma vs. normal	1.875	2.70E-04	7.056	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	1.987	1.25E-04	5.321	Kaiser Colon [25]
S100A2L2	NA	NA	NA	NA	NA
S100A8	Colorectal carcinoma vs. normal	6.313	5.37E-06	5.126	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	2.29	3.89E-04	4.478	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	2.723	1.80E-02	2.488	Kaiser Colon [25]
S100A9	Colorectal carcinoma vs. normal	3.941	1.14E-08	6.784	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	1.951	6.05E-04	5.139	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	2.097	1.80E-02	2.455	Kaiser Colon [25]
S100A10	Colorectal adenocarcinoma vs. normal	-1.169	9.97E-01	-2.95	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	-1.075	7.60E-01	-0.719	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	-1.107	6.66E-01	-0.444	Kaiser Colon [25]
S100A11	Colorectal adenocarcinoma vs. normal	2.282	2.21E-11	10.392	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	1.734	4.00E-03	4.425	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	1.775	3.00E-03	4.487	Kaiser Colon [25]
S100A12	Colorectal carcinoma vs. normal	1.695	4.00E-03	2.743	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	1.103	1.97E-01	0.856	Ki Colon [28]
S100A13	Colorectal carcinoma vs. normal	1.199	4.60E-02	1.721	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	1.133	1.51E-01	1.102	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	1.081	3.13E-01	0.501	Kaiser Colon [25]
S100A14	Colorectal carcinoma vs. normal	-1.655	1.00E+00	-3.731	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	-2.18	1.00E+00	-8.84	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	-2.143	1.00E+00	-5.957	Kaiser Colon [25]
S100A16	Colon adenocarcinoma vs. normal	-1.573	9.92E-01	-3.348	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	-1.549	9.91E-01	-3.084	Kaiser Colon [25]
S100B	Colorectal carcinoma vs. normal	-1.065	6.46E-01	-0.378	Skrzypczak Colorectal [27]
S100P	Colorectal carcinoma vs. normal	3.212	1.91E-06	5.587	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	4.911	3.00E-03	4.798	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	4.879	2.00E-03	4.233	Kaiser Colon [25]
S100G	Colorectal adenocarcinoma vs. normal	1.025	2.08E-01	0.821	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	1.19	1.20E-01	1.202	Notterman Colon [29]
	Rectal adenocarcinoma vs. normal	1.025	1.10E-02	2.325	Gaedcke Colorectal [26]
S100Z	Colorectal carcinoma vs. normal	1.059	4.50E-02	1.738	Skrzypczak Colorectal [27]
	Colon adenocarcinoma vs. normal	1.138	0.081	1.698	Kaiser Colon [25]
	Rectal adenocarcinoma vs. normal	1.115	1.13E-01	1.398	Kaiser Colon [25]