Research Article
Histopathology of Cutaneous Leishmaniasis Caused by Leishmania donovani in Sri Lanka
Table 2
Dermal changes of lesions among patients with cutaneous leishmaniasis.
| | Dermal change | Category | Number (%) |
| | Type of inflammatory cells | Lymphocytes | Absent | 0 (0) | | Fewer in number to other cells | 3 (6) | | Equal in number to other cells | 40 (80) | | Dominates other cells | 40 (80) | | Plasma cells | Absent | 5 (10) | | Fewer in number to other cells | 27 (54) | | Equal in number to other cells | 18 (36) | | Dominates other cells | 0 (0) | | Macrophages | Absent | 0 (0) | | Fewer in number to other cells | 3 (6) | | Equal in number to other cells | 25 (50) | | Dominates other cells | 22 (44) | | Neutrophils | Absent | 16 (32) | | Fewer in number to other cells | 32 (64) | | Equal in number to other cells | 2 (4) | | Dominates other cells | 0 (0) | | Eosinophils | Absent | 43 (86) | | Fewer in number to other cells | 7 (14) | | Equal in number to other cells | 0 (0) | | Dominates other cells | 0 (0) | | Multinucleated giant cells | Present | 13 (26) | | Absent | 37 (74) |
| | Nature of inflammatory infiltrate | Macrophage predominant | 22 (44) | | Lymphocyte predominant | 7 (14) | | Lymphoplasmacytic | 1 (2) | | Lymphohistiocytic | 9 (18) | | Lymphohistioplasmacytic | 11 (22) |
| | Degree of inflammation | Mild | 5 (10) | | Moderate | 16 (32) | | Extensive | 29 (58) |
| | Necrosis | Absent | 40 (80) | | Focal | 10 (20) | | Diffuse | 0 (0) |
| | Neuritis | Absent | 45 (90) | | Present | 5 (10) |
| | Granuloma | Absent | 9 (18) | | Ill-defined granuloma | 19 (38) | | Well defined granuloma | 22 (44) |
| | Pattern of inflammation | Diffuse infiltrate | 9 (18) | | Ill-defined histiocytic infiltrate | 19 (38) | | Well defined granuloma | 22 (44) |
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