Database Mining of Genes of Prognostic Value for the Prostate Adenocarcinoma Microenvironment Using the Cancer Gene Atlas

Figure 2

Comparison of prostate adenocarcinoma (PRAD) gene expression profile according to immune and stromal scores. The average linkage method and Pearson distance measurement method were used to draw the heat maps. The genes with high expression are shown in red, those with low expression are shown in green, and those with the same expression are shown in black. (a) A heat map of DEGs (, ) between the high and low immune score groups. (b) Heat map of DEGs (, ) between the high and low stromal score groups. (c, d) Venn diagrams showed the (c) upregulated genes for the high immune and high stromal groups and the overlap representing genes common to the high stromal group versus the high immune group (d) downregulated genes for the high immune and high stromal groups and the overlap representing genes common to the high stromal group versus the high immune group.