Therapeutic Efficacy of Intratendinous Delivery of Dexamethasone Using Porous Microspheres for Amelioration of Inflammation and Tendon Degeneration on Achilles Tendinitis in Rats

Figure 4

Masson’s trichrome staining at 5 weeks after collagenase (Col (I)) injection into tendon tissues and 4 weeks after treatment with PMSs, DEX (1%)/PMSs, DEX (5%)/PMSs, and DEX (10%)/PMSs. Groups are divided as follows: (a) control (no treatment); (b) Col (I); (c) Col (I) + PMSs; (d) Col (I) + DEX (1%)/PMSs; (e) Col (I) + DEX (5%)/PMSs; (f) Col (I) + DEX (10%)/PMSs. Scale bar: 100 µm. Red: collagen fibers; blue: collagen matrix collapse.

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