Association between the MMP-1-1607 1G/2G Polymorphism and Osteoarthritis Risk: A Systematic Review and Meta-Analysis

Table 2

Genotype and allele distributions of MMP-1-1607 1G/2G (rs1799750) polymorphism in the included studies.

Author	Case		Control			Association findings in case
	2G/1G	2G2G/2G1G/1G1G	2G/1G	2G2G/2G1G/1G1G
Barlas	193/119	68/57/31	128/34	52/24/5	0.34	1G allele↑, 1G/1G, and 1G/2G genotype↑
Planello	134/96	45/44/26	118/116	26/66/25	0.16	1G allele↓, 1G/1G, and 1G/2G genotype↑
Abd-Allah	100/100	27/46/27	60/140	10/40/50	0.63	2G allele↑, 2G/2G, and 1G/2G genotype↑
Lepetsos	190/120	63/64/28	152/126	47/58/34	0.06	NS
Luo	223/189	66/91/49	151/219	29/93/63	0.58	NA
Yang	272/142	92/88/27	285/129	98/8920	0.97	NS
Geng	306/306	76/154/76	323/479	61/201/139	0.40	2Gallele↑, 2G/2G genotype↑

MMP: matrix metalloproteinase; HWE: Hardy-Weinberg equilibrium.