Lanthanum Chloride Causes Neurotoxicity in Rats by Upregulating miR-124 Expression and Targeting PIK3CA to Regulate the PI3K/Akt Signaling Pathway

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Gene name</td><td class="align_center">The primer sequences (5<svg height="11.4859pt" id="M8" style="vertical-align:-0.04979992pt" version="1.1" viewbox="-0.0498162 -11.4361 3.89517 11.4859" width="3.89517pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M310 541L304 571C290 586 211 619 185 610L80 76L131 52L310 541Z"></path></g></svg>⟶3<span class="nowrap"><svg height="11.4859pt" id="M9" style="vertical-align:-0.04979992pt" version="1.1" viewbox="-0.0498162 -11.4361 3.89517 11.4859" width="3.89517pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M310 541L304 571C290 586 211 619 185 610L80 76L131 52L310 541Z"></path></g></svg>)</span></td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">miR-124 upstream primer</td><td class="align_center">GCTAAGGCACGCGGTG</td></tr><tr><td class="align_left">miR-124 downstream primer</td><td class="align_center">GTGCAGGGTCCGAGGT</td></tr><tr><td class="align_left">U6 upstream primer</td><td class="align_center">CTCGCTTCGGCAGCACA</td></tr><tr><td class="align_left">U6 downstream primer</td><td class="align_center">AACGCTTCACGAATTTGCGT</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>The primer sequences of miR-124 and U6.</div>

BioMed Research International

tab1

Table 1

Table 1: Lanthanum Chloride Causes Neurotoxicity in Rats by Upregulating miR-124 Expression and Targeting PIK3CA to Regulate the PI3K/Akt Signaling Pathway 

Table 1 | Lanthanum Chloride Causes Neurotoxicity in Rats by Upregulating miR-124 Expression and Targeting PIK3CA to Regulate the PI3K/Akt Signaling Pathway 