Review Article

Prognostic Role of Optic Nerve Sheath Diameter for Neurological Outcomes in Post-Cardiac Arrest Patients: A Systematic Review and Meta-Analysis

Table 1

Characteristics of the included studies.

Author (year)Publication yearCountryDesignMethod of ONSD measurementTime of ONSD measurementSample sizeCutoff (mm)ONSD
Poor prognosisGood prognosis

Chae et al. [4]2016KoreaRetrospectiveCTWithin 6 h after ROSC1195.95.8 (0.6)5.6 (0.5)
Chelly et al. [5]2016FranceProspectiveUltrasoundAt 24 h after CA365.57.2 (6.8–7.4)6.5 (6.0–6.8)
Ertl et al. [6]2019GermanyProspectiveUltrasoundAt 24 h after CA495.75
Kim et al. [7]2014KoreaRetrospectiveCTWithin 24 h after ROSC916.21
Park et al. [8]2019KoreaProspectiveUltrasoundAt 24 h after ROSC364.90
Ryu et al. [9]2017KoreaRetrospectiveCTWithin 24 h after ECPR426.696.07 (5.71–6.64)5.57 (5.14–5.98)
Ueda et al. [10]2015JapanRetrospectiveUltrasoundAt 12–72 h after CA175.46.1 (5.4–7.2)5.0 (4.4–6.1)
You et al. [11]2018KoreaRetrospectiveUltrasoundBefore TTM835.115.29 (4.50–5.76)4.48 (4.27–5.09)

CA: cardiac arrest; ECPR: extracorporeal cardiopulmonary resuscitation; NA: not available; ONSD: optic nerve sheath diameter; ROSC: return of spontaneous circulation; TTM: target temperature management.