| | Study (year) | Type of breast cancer | Type of BPs | Definition of exposure | Measure of BP use | Average exposure period (years) | Adjustment for covariates |
| | Cardwell (2011) [6] | Breast cancer | BP | One or more prescriptions of oral BPs | Medical record | 4.5 | Smoking, alcohol, BMI, HRT, oral steroids, NSAIDs, calcium, and vitamin D | | Chiang (2012) [7] | Breast cancer | ALN | Prescriptions of oral ALN | Medical record | 4.8 | Age, hypertension, diabetes, COPD, estrogen, dyslipidemia, CKD, CAD, colorectal polyp, benign breast disease, obesity, and statin use | | Chlebowski (2010) [8] | Invasive breast cancer & DCIS | BP | One or more oral BPs | Self-report | 7.8 | Age, ethnicity, smoking, alcohol, physical activity, BMI, mammogram, estrogen, progesterone, calcium, vitamin D, hip fracture, and Gail 5 y risk of breast cancer | | Fournier (2017) [9] | Invasive breast cancer & DCIS | BP | One or more oral BPs | Self-report | 7.2 | Age, BMI, time since menopause, HRT, calcium, and vitamin D | | Hue (2014) [10] | Breast cancer | ALN & ZA | Oral ALN or ZA | Medical record | 3.8 | Age, BMI, smoking, ethnicity, age at first pregnancy, and family of breast cancer history | | Lee (2012) [11] | Breast cancer | ALN | Prescriptions of oral ALN | Medical record | 3.04 | Age | | Monsees (2011) [12] | Contralateral breast cancer | BP & ALN | One or more BPs | Medical record | ≥1 | Progesterone receptor, status of the first primary breast cancer, height, weight, BMI, diagnosed with osteoporosis or osteopenia, mammography, therapies received or first breast cancer, chemotherapy, radiation, parity, menopausal status, alcohol, smoking, HRT, and first-degree family history of breast cancer | | Newcomb (2010) [13] | Invasive breast cancer | BP | One or more BPs | Self-report | 5 | Age, parity, age at first live birth, family history of breast cancer, BMI, menopausal status, age at menopause, type of hormone use, mammography, osteoporosis, smoking, height, HRT, and self-reports of medication use | | Rennert (2010) [14] | Breast cancer | BP & ALN | One or more prescriptions of oral BPs | Medical record | 5 | Family of breast cancer history, age, sports activity, Jewish ethnic group, fruit vegetable consumption, BMI, statin, aspirin, calcium, vitamin D, HRT, red meat consumption, number of pregnancies, months of breast feeding, and age at first pregnancy | | Vestergaard (2011) [16] | Breast cancer | ALN, CLN, ETN, & RIN | One or more dispensations of oral BPs | Medical record | NA | Use of systemic hormone therapy, irradiation, chemotherapy, and alcoholism | | Vinogradova (2013) [15] | Breast cancer | BP, ALN, ETN, & RIN | One or more prescriptions of oral BPs | Medical record | 1.67 | BMI, smoking, alcohol, ethnicity, comorbidity, and use of other drugs |
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