Clinical Study

Validation of the Combined Model Based on Platelet Count and Albumin to Rule out High-Risk Varices in Liver Cirrhosis

Table 2

Comparison of the total population with HRV vs. the population without HRV.

VariablesHRV, Non-HRV,

Male (%)30 (63.8)157 (64.1)0.974a
Age (years)50 (44.5-58)53 (43-61)0.697
BMI22 (21.1-23.4)23.2 (21.5-25.2)0.126
Etiology0.363a
 Hepatitis B34140
 Hepatitis C04
 PBC17
 Alcohol210
 Others1083
Child-Pugh0.291a
 A37208
 B1037
Platelets (103/μL)77 (57.5-96)119 (90-169)<0.001
ALT (IU/L)29.3 (21-37)26.1 (18-42)0.465
ALB (g/L)37.2 (33.2-40.9)41.6 (36.8-44.4)<0.001
Bilirubin (μM/L)22.3 (15.5-33.2)20 (14-28.1)0.129
INR1.3 (1.2-1.4)1.2 (1.1-1.3)<0.001
TE LSM (kPa)30.1 (14-35.6)19.6 (12-34.8)0.405

Statistical comparison between the presence and absence of high-risk varices using Mann–Whitney test unless indicated. aStatistical comparison between the presence and absence of high-risk varices using Chi-square test or Fisher’s exact test. TE was available in 90 patients. Abbreviations: ALB: albumin; HCV: hepatitis C virus; INR: international normalized ratio; LSM: liver stiffness measurement; PBC: primary biliary cholangitis; TE: transient elastography.