Safety and Prognostic Impacts of Ovarian Preservation during Radical Hysterectomy for Early-Stage Adenocarcinoma and Adenosquamous Cervical Cancer

Table 3

Multivariate analysis of 5-year recurrence-free survival in patients aged <50 years.

Characteristics	Full model			Reduced model
	HR	95% CI	value	HR	95% CI	value
FIGO stage			0.023			0.005
IA2	1			1
	Inf	(0-Inf)		Inf	(0-Inf)
	Inf	(0-Inf)		Inf	(0-Inf)
LVSI			1.000
No	1	—
Yes	0.99	0.22-4.48
Parametrial invasion			0.596
No	1	—
Yes	1.47	(0.36-6.11)
LN metastasis			0.018			<0.001
No	1	—		1	—
Yes	5.15	1.39-19.10		9.77	(3.32-28.72)
Vaginal margin involvement			0.298
No	1	—
Yes	2.61	0.45-15.18
DSI			0.526
No	1	—
Yes	0.66	0.18-2.44
Adjuvant treatment			0.316
No	1	—
RT	2.73	0.67-11.13
CCRT	3.82	0.37-38.97
Ovarian preservation			0.454			0.529
No	1	—		1	—
Yes	0.72	0.30-1.73		0.76	0.33-1.78

FIGO: The International Federation of Gynecology and Obstetrics; LVSI: lymph-vascular space invasion; LN: lymph node; DSI: deep stromal invasion; RT: radiotherapy; CCRT: concurrent chemoradiation.