Safety and Prognostic Impacts of Ovarian Preservation during Radical Hysterectomy for Early-Stage Adenocarcinoma and Adenosquamous Cervical Cancer

Table 4

Multivariate analysis of 5-year overall survival in patients aged <50 years.

Characteristics	Full model			Reduced model
	HR	95% CI	value	HR	95% CI	value
FIGO stage			0.037			0.014
IA2	1			1
	Inf	(0-Inf)		Inf	(0-Inf)
	Inf	(0-Inf)		Inf	(0-Inf)
LVSI			0.802
No	1	—
Yes	1.22	0.26-5.73
Parametrial invasion			0.835
No	1	—
Yes	1.18	0.25-5.67
LN metastasis			0.022			<0.001
No	1	—		1	—
Yes	8.21	1.30-51.77		5.2	(1.30-21.40)
DSI			0.481
No	1	—
Yes	0.56	0.11-2.97
Adjuvant treatment			0.127
No	1	—
RT	3.24	0.52-20.07
CCRT	12.4	1.09-140.34
Ovarian preservation			0.703			0.966
No	1	—		1	—
Yes	0.82	0.29-2.32		0.98	0.36-2.65

FIGO: The International Federation of Gynecology and Obstetrics; LVSI: lymph-vascular space invasion; LN: lymph node; DSI: deep stromal invasion; RT: radiotherapy; CCRT: concurrent chemoradiation.