Screening of T Cell-Related Long Noncoding RNA-MicroRNA-mRNA Regulatory Networks in Non-Small-Cell Lung Cancer

Figure 4

GO and KEGG enrichment analysis of (a, b) CD8(+) T cell-related DEGs and (c, d) memory-activated CD4(+) T cell-related DEGs. ClusterProfiler was used to analyze the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment involving both, upregulated and downregulated genes. The GO analysis included Biological Process (BP), Cellular Component (CC) and Molecular Function (MF). value < 0.05 and were considered significant enrichment. The CD8(+) T cell-related DEGs were enriched in 338 GO terms and 369 KEGG pathways. The memory-activated CD4(+) T cell-related DEGs were enriched in 12 GO terms and 14 KEGG pathways. DEGs represent differentially expressed genes.

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