Significant Association of rs2147555 Genetic Polymorphism in the EDNRB Gene with Hirschsprung Disease in Southern Chinese Children

Table 1

General clinical characteristics of the HSCR case-control cohort.

Characteristic	Cases ()	Controls ()
Gender (male/female)	1230/240	966/506	0.001
Onset month		N/A	—
S-HSCR (%)	1034 (70.3%)	N/A	—
L-HSCR (%)	295 (20.1%)	N/A	—
TCA (%)	82 (5.6%)	N/A	—
TIA (%)	3 (0.2%)	N/A	—
Presurgery enteritis (%)	261 (17.8%)	N/A	—
Postsurgery enteritis (%)	249 (16.9%)	N/A	—

Onset month (): age (month) of onset for HSCR cases; is derived from an unpaired Student’s -test or Pearson’s chi-square test. S-HSCR: short-segment HSCR; L-HSCR: long-segment HSCR; TCA: total colonic aganglionsis; TIA: total intestinal aganglionosis.