A Novel Three-miRNA Signature Identified Using Bioinformatics Predicts Survival in Esophageal Carcinoma

Table 2

Association between three miRNAs and clinical features.

Variable	miR-431-5p expression			miR-769-5p expression			miR-1301-3p expression
	Low	High	value	Low	High	value	Low	High	value
Age, yrs			0.277			0.642			0.003
<60	34	41		36	39		28	47
≥60	50	43		48	45		56	37
T Stage			0.342			0.678			0.014
T1	15	8		11	12		18	5
T2	21	24		26	19		22	23
T3	45	46		43	48		42	49
T4	3	6		4	5		2	7
Lymph node status			0.871			0.399			0.463
N0	35	34		38	31		39	30
N1–3	42	43		41	44		43	42
Distant metastasis			0.164			0.320			0. 073
M0	72	65		71	66		73	64
M1	12	19		13	18		11	20
Histologic grade			0.757			0.005			0.005
Gx + G1	46	44		54	36		55	35
G2 + G3	38	40		30	48		29	49
Pathologic stage			0.048			0.644			0.105
I	11	4		9	6		11	4
II	36	40		39	37		40	36
III	33	28		30	31		28	33
IV	4	12		6	10		5	11

Yrs: years.