Low Stroke Volume Index in Healthy Young Men Is Associated with the Incidence of Acute Mountain Sickness after an Ascent by Airplane: A Case-Control Study
Table 1
Basic characteristics, physiological parameters, left ventricular function, and mitral Doppler flow in subjects at sea level or at HA with or without AMS.
Variables
Sea level ()
High altitude ()
ALL
AMS (-)
AMS (+)
()
()
()
Basic characteristics
Age (years)
23 (20-26)
23 (20-26)
22 (20-24)
23 (20-27)##
Height (cm)
172 (168-175)
172 (168-175)
172 (169-175)
172 (168-175)
Weight (kg)
64 (59-69)
64 (59-69)
64 (60-68)
64 (58-70)
BMI (kg·cm-2)
21.6 (20.2-23.2)
21.5 (20.2-23.1)
21.6 (20.2-23.1)
21.5 (20.1-23.2)
BSA (m2)
1.71 (1.63-1.79)
1.71 (1.63-1.79)
1.71 (1.64-1.78)
1.71 (1.62-1.80)
Smoking (, %)
378 (67.6%)
403 (68.4%)
240 (68.4%)
163 (68.5%)
Drinking (, %)
353 (63.1%)
371 (63.0%)
225 (64.1%)
146 (61.3%)
Physiological parameters
HR (bpm)
66 (59-70)
81 (73-89)
79 (71-88)
83 (77-91)##
SBP (mmHg)
115 (108-122)
118 (111-124)
118 (111-123)
117 (109-124)
DBP (mmHg)
74 (68-80)
78 (72-85)
78 (72-85)
78 (72-84)
MAP (mmHg)
87 (82-94)
91 (85-97)
91 (86-98)
91 (84-96)
SpO2 (%)
98.0 (98.0-99.0)
89.0 (87.0-91.0)
89.0 (88.0-91.0)
88.0 (86.0-90.0)
LV function
ESVi (ml/m2)
23.0 (20.0-27.8)
22.4 (18.8-25.9)
22.7 (19.3-26.3)
21.6 (18.5-25.6)
EDVi (ml/m2)
65.6 (58.0-74.7)
59.4 (51.8-68.2)
63.4 (56.5-71.5)
52.6 (45.2-61.5)##
SVi (ml/m2)
40.9 (34.9-50.3)
37.0 (30.2-43.3)
40.7 (35.7-45.6)
30.0 (26.0-36.4)##
LVEF (%)
63.7 (62.4-66.5)
66.6 (64.0-70.0)
66.7 (64.0-70.0)
66.5 (64.0-69.0)
CI (l/min/m2)
2.7 (2.2-3.3)
3.0 (2.4-3.5)
3.2 (2.7-3.8)
2.5 (2.2-3.1)##
Mitral Doppler flow
E-wave velocity (cm/s)
79 (69-92)
75 (65-88)
79 (69-92)
69 (61-80)##
A-wave velocity (cm/s)
48 (42-54)
55 (48-63)
54 (47-62)
55 (48-65)
E/A ratio
1.71 (1.39-2.05)
1.38 (1.11-1.75)
1.48 (1.22-1.86)
1.23 (1.02-1.55)##
Values are expressed as the median (interquartile range) or (%). AMS: acute mountain sickness; BMI: body mass index; BSA: body surface area; HR: heart rate; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; SpO2: oxygen saturation; ESVi: end-systolic volume index; EDVi: end-diastolic volume index; SVi: stroke volume index; LVEF: left ventricular ejection fraction; CI: cardiac index; E: peak flow velocity of the early mitral filling wave; A: peak flow velocity of late mitral filling wave; bpm: beats per minute. , vs. subjects at sea level and # and ## vs. AMS (-) subjects.
