Expression, Prognosis, and Immune Infiltrates Analyses of E2Fs in Human Brain and CNS Cancer

Table 1

The significant changes of the E2F expression in transcription level between different types of brain and CNS cancer and normal brain and CNS tissues (Oncomine database).

	Type of breast cancer versus normal breast tissue	Fold change	value	-test	Source and/or reference
E2F1	NA	NA	NA	NA	NA
E2F2	NA	NA	NA	NA	NA
E2F3	NA	NA	NA	NA	NA
E2F4	NA	NA	NA	NA	NA
E2F5	Anaplastic oligodendroglioma	2.425	3.64e−10	9.420	French Brain Statistics [28]
	Anaplastic astrocytoma	2.545	1.45e−7	6.181	Sun Brain Statistics [29]
	Oligodendroglioma	2.580	1.99e−7	5.707	Sun Brain Statistics [29]
	Glioblastoma	2.877	1.78e−9	7.518	Sun Brain Statistics [29]
	Glioblastoma	2.016	1.59e−7	10.319	Murat Brain Statistics [30]
E2F6	NA	NA	NA	NA	NA
E2F7	Glioblastoma	4.632	1.08e−28	17.833	Murat Brain Statistics [30]
	Glioblastoma	5.823	1.31e−21	13.696	Sun Brain Statistics [29]
	Anaplastic oligodendroglioma	2.282	4.46e−5	4.698	French Brain Statistics [28]
E2F8	Anaplastic astrocytoma	4.196	8.33e−6	4.893	Sun Brain Statistics [29]
	Glioblastoma	7.097	1.25e−9	8.349	Sun Brain Statistics [29]
	Oligodendroglioma	3.341	9.18e−6	5.003	Sun Brain Statistics [29]

NA: not available; TCGA: The Cancer Genome Atlas.