Identification of 5 Gene Signatures in Survival Prediction for Patients with Lung Squamous Cell Carcinoma Based on Integrated Multiomics Data Analysis

Table 5

GSEA analyzed significantly enriched KEGG pathways in high-risk and low-risk groups.

Name	Size	ES	NES	NOM -val	FDR -val	FWER -val
KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION	243	-0.609	-2.002	0.0001	0.055	0.037
KEGG_LEISHMANIA_INFECTION	64	-0.709	-1.985	0.0001	0.039	0.052
KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	68	-0.726	-1.969	0.0001	0.035	0.064
KEGG_HEMATOPOIETIC_CELL_LINEAGE	84	-0.708	-1.967	0.0001	0.026	0.064
KEGG_CELL_ADHESION_MOLECULES_CAMS	122	-0.623	-1.961	0.002	0.023	0.07
KEGG_VIRAL_MYOCARDITIS	67	-0.636	-1.933	0.0001	0.028	0.1
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION	108	-0.551	-1.920	0.002	0.029	0.115
KEGG_AUTOIMMUNE_THYROID_DISEASE	49	-0.710	-1.817	0.002	0.075	0.259
KEGG_CHEMOKINE_SIGNALING_PATHWAY	178	-0.491	-1.799	0.020	0.080	0.3
KEGG_ASTHMA	27	-0.790	-1.795	0.0001	0.075	0.306
KEGG_TYPE_I_DIABETES_MELLITUS	40	-0.747	-1.791	0.008	0.070	0.316
KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES	14	-0.681	-1.732	0.008	0.107	0.454
KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION	45	-0.727	-1.720	0.009	0.109	0.476
KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY	127	-0.510	-1.710	0.018	0.112	0.505
KEGG_ALLOGRAFT_REJECTION	34	-0.807	-1.709	0.006	0.105	0.508
KEGG_ECM_RECEPTOR_INTERACTION	82	-0.592	-1.708	0.023	0.100	0.511
KEGG_JAK_STAT_SIGNALING_PATHWAY	147	-0.468	-1.701	0.014	0.100	0.525
KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION	78	-0.581	-1.692	0.033	0.102	0.546
KEGG_LYSOSOME	115	-0.483	-1.683	0.024	0.103	0.562
KEGG_GRAFT_VERSUS_HOST_DISEASE	36	-0.780	-1.669	0.016	0.109	0.595
KEGG_FOCAL_ADHESION	189	-0.484	-1.664	0.031	0.109	0.607
KEGG_PRION_DISEASES	35	-0.487	-1.662	0.006	0.106	0.613
KEGG_RENIN_ANGIOTENSIN_SYSTEM	16	-0.603	-1.655	0.028	0.107	0.624
KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY	54	-0.489	-1.608	0.041	0.142	0.722
KEGG_HISTIDINE_METABOLISM	26	-0.484	-1.592	0.046	0.154	0.757
KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	82	-0.445	-1.583	0.037	0.157	0.776
KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	99	-0.441	-1.574	0.048	0.160	0.787
KEGG_OTHER_GLYCAN_DEGRADATION	15	-0.587	-1.532	0.060	0.201	0.852
KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION	47	-0.415	-1.515	0.026	0.216	0.874
KEGG_BASAL_TRANSCRIPTION_FACTORS	34	0.584	1.895	0.004	0.141	0.131
KEGG_NUCLEOTIDE_EXCISION_REPAIR	44	0.607	1.855	0.004	0.124	0.2
KEGG_CELL_CYCLE	112	0.531	1.841	0.004	0.100	0.231
KEGG_HOMOLOGOUS_RECOMBINATION	24	0.700	1.831	0.004	0.082	0.246
KEGG_SPLICEOSOME	90	0.605	1.811	0.004	0.081	0.283
KEGG_DNA_REPLICATION	32	0.732	1.767	0.004	0.106	0.392
KEGG_MISMATCH_REPAIR	23	0.674	1.718	0.016	0.141	0.503
KEGG_BASE_EXCISION_REPAIR	33	0.609	1.680	0.024	0.165	0.59
KEGG_RNA_DEGRADATION	47	0.530	1.676	0.012	0.152	0.6
KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS	22	0.570	1.638	0.024	0.179	0.675
KEGG_RNA_POLYMERASE	28	0.556	1.622	0.033	0.181	0.711