H-Type Hypertension Is a Risk Factor for Cerebral Small-Vessel Disease

Table 2

Clinical baseline characteristics of participants according to H-type hypertension.

Variables	Control group (n = 76)	Isolated HBP (n = 112)	Isolated HHcy (n = 53)	H-type HBP group (n = 88)	χ^2/F
Age	55.78 ± 13.36	63.35 ± 12.82	63.45 ± 13.03	66.44 ± 13.15	9.624	0.000
Male	49 (64.5%)	65 (58.0%)	36 (67.9%)	70 (79.5%)	10.551	0.014
Diabetes mellitus	7 (9.3%)	32 (28.6%)	1 (1.9%)	20 (22.7%)	22.647	0.000
Cardiac diseases	12 (15.8%)	16 (14.3%)	11 (21.2%)	19 (21.6%)	2.429	0.488
Systolic pressure	132.33 ± 13.04	148.80 ± 17.86	134.39 ± 14.42	147.19 ± 19.24	21.022	0.000
Diastolic pressure	79.08 ± 9.69	85.78 ± 11.75	79.66 ± 10.74	82.98 ± 14.48	5.900	0.001
TC (mmol/l)	4.11 ± 0.92	4.28 ± 1.08	3.99 ± 0.83	4.39 ± 1.02	2.274	0.080
TG (mmol/l)	1.34 ± 0.60	1.72 ± 1.28	1.17 ± 0.46	1.64 ± 1.19	4.453	0.004
HDL-C (mmol/l)	1.19 ± 0.28	1.25 ± 0.34	1.17 ± 0.30	1.21 ± 0.29	1.222	0.302
LDL-C (mmol/l)	2.38 ± 0.80	2.54 ± 0.89	2.31 ± 0.70	2.63 ± 0.75	2.347	0.073
Glucose (mmol/l)	5.80 ± 2.28	6.90 ± 2.70	5.24 ± 0.99	6.27 ± 1.91	7.876	0.000
Urid acid (U/L)	281.40 ± 74.02	283.55 ± 78.97	313.71 ± 90.11	344.58 ± 106.09	10.187	0.000
Hs-CRP (mg/L)	4.19 ± 6.27	4.24 ± 4.69	4.18 ± 4.65	6.12 ± 6.77	2.441	0.064
Hcy (μmol/l)	8.00 ± 2.29	8.81 ± 2.49	22.60 ± 20.86	22.46 ± 27.68	19.049	0.000

Note: , vs. control group, , vs. isolated hypertension group, , vs. isolated HHcy group. HBP is the abbreviation of hypertension.