Cardiac Ameliorative Effect of Moringa oleifera Leaf Extract in High-Fat Diet-Induced Obesity in Rat Model

Table 6

Lipid peroxidation levels (TBARS), nonenzymatic antioxidant levels (TSH), and enzymatic antioxidant activities (glutathione peroxidase, catalase, and superoxide dismutase) in the hearts of the different groups.

Parameters	C	HFD	MEML 200	MEML 400
TBARS (nmol/mg protein)	0.61 ± 0.34	1.31 ± 0.23	1.05 ± 0.49^++	0.77 ± 0.3^++
SOD (U/mg of protein)	10.01 ± 0.26	6.95 ± 0.08	7.82 ± 0.21^+	8.97 ± 1.09^++
CAT (μmol/min/mg of protein)	14.89 ± 2.11	9.52 ± 1.2	11.75 ± 0.48^++	13.01 ± 0.7^++
GPx (μmol GSH oxidized/min/mg of protein)	6.83 ± 0.65	4.01 ± 1.1	5.1 ± 1.8^++	6.05 ± 0.04^++
TSH (U/mg protein)	1.92 ± 0.1	0.51 ± 0.02	0.72 ± 0.33^++	0.89 ± 0.1^++

Values are expressed as (). , versus the control group (C). ⁺, ⁺⁺ versus the high-fat diet group (HFD). C: control rats; HFD: rats fed with high-fat diet; MEML 200: rats fed a high-fat diet and treated with methanolic extract of M. oleifera leaves (200 mg/kg); MEML 400: rats treated with methanolic extract of M. oleifera leaves (400 mg/kg) along with high-fat diet for 12 weeks.