Review Article

Prognostic Value of Pretreatment Albumin-to-Alkaline Phosphatase Ratio in Cancer: A Meta-Analysis

Table 1

The characteristics of included studies.

Study (year)CountryCancer typeSample capacityAge (years)Gender ratioTreatmentOutcomeFollow-up (months)Cutoff valueAnalysisNOS

Nie et al. [11]ChinaMetastatic NPC209Median 45 (14-72)179/30With chemotherapyOS, PFSMedian 16.6 (1-66.6)0.447M8
Cai et al. [18]ChinaAdvanced HCC237Median 56 (45-66)206/31Without standard treatmentOS>120.38M8
Chen et al. [10]ChinaHCC372Median 52 (44-61)348/24With chemotherapyOS>600.439M8
202Median 56 (45-65)176/26With chemotherapyOS>600.439M8
82Median 55 (44-63)73/9With chemotherapyOS>600.439M8
Tan et al. [13]ChinaUTUC692398/294With surgeryOS, CSS, RFSMedian 42 (20-75)0.58M8
Long et al. [14]ChinaNonmetastatic breast cancer746NA0/746With surgeryOS>600.525M8
Kim et al. [19]KoreaNonmetastatic NPC100NA78/22MixedOS, PFS, LRRFS, DMFSMedian 50.60.4876M8
Li et al. [15]ChinaMetastatic NSCLC290Mean 55 (25-90)210/75With chemotherapyOS>600.84M8
Li et al. [20]ChinaLung cancer390243/147With surgeryOS, DFSMedian 50.0 (12-66)0.57M8
Li et al. [21]ChinaLimited stage SCLC122Median 58244/58With radiotherapyOS, PFSMedian 21.3 (17.9-25.2)0.61U6
Xia et al. [22]ChinaNonmetastatic RCC419266/153With surgeryOS, CSSMedian 50.0 (30.4-83.0)0.39M8
204127/77With surgeryOS, CSSMedian 50.2 (29.8-83.1)0.39U6
Xiong et al. [23]ChinaCCA303Median 59 (29-83)168/135With surgeryOS, PFSMedian 21.00.41M8
Zhang et al. [24]ChinaCervical carcinoma230Median 55 (29-79)101/65With surgeryOS, DFSMedian 81 (12-137)0.68M8
Zhang et al. [12]ChinaNSCLC496Median 60 (34-81)334/162With surgeryOS, DFSMedian 47.0 (2.0-96.0)0.64M8
Li et al. [25]ChinaHCC149Mean 51.26141/8With surgeryOS, RFS>600.38U and M7
61Mean 52.1557/4With surgeryOS, RFS>600.38U6
Li et al. [26]ChinaHCC188Median 52.3 (22-77)161/27With surgeryOS, RFSMedian 46.50.4M8
Zhou et al. [27]ChinaED-SCLC224197/27MixedOSNA0.35M8