Catalpol Attenuates Hepatic Steatosis by Regulating Lipid Metabolism via AMP-Activated Protein Kinase Activation

Figure 4

Catalpol treatment reduces body weight gain and elevates the serum levels of lipids and hepatic enzymes in high-fat diet- (HFD-) fed mice. C57BL/6J mice were fed a normal diet or HFD and treated with saline, atorvastatin calcium (ATC), or different doses of catalpol daily for 18 weeks. (a) Body weight changes. (b–e) Serum levels of triglyceride (TG), total cholesterol (TC), alanine aminotransferase (ALT), and aspartate aminotransferase (AST). Data are presented as the (). vs. the Normal group; ^#, ^## vs. the HFD group.

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