AKNA Is a Potential Prognostic Biomarker in Gastric Cancer and Function as a Tumor Suppressor by Modulating EMT-Related Pathways

Figure 4

The correlation of AKNA and circTRNC18/miR-762 axis in GC. (a, b) One of the most possible miRNA targeted AKNA was predicted by Targetscan and TargetMiner. AKNA had multiple potential binding sites with miR-762. (c) The expression of circTRNC18 and miR-762 in GC cell lines and GES-1 was detected by qRT-PCR. Data are . , . (d) The expression of miR-762 in 32 GC and paired normal tissues was detected by qRT-PCR. Data are . . (e) The expression of circTRNC18 in 32 GC and paired normal tissues was detected by qRT-PCR. Data are . . (f) Pearson’s correlation coefficient was calculated between miR-762 and circTRNC18 expression in GC. , . (g) Pearson’s correlation coefficient was calculated between miR-762 and AKNA expression in GC. , .

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