Identification of FOS as a Candidate Risk Gene for Liver Cancer by Integrated Bioinformatic Analysis

Table 2

Top 10 genes with high degree in miRNA-gene-pathway network.

Gene symbol	Expression	Degree	Average shortest path length	Betweenness centrality	Closeness centrality	Clustering coefficient	Topological coefficient
FOS	Up_gene	54	1.787234	0.138354	0.559524	0.378756	0.3768
LAMC2	Up_gene	13	2.308511	0.021807	0.43318	0.692308	0.485577
CALML3	Down_gene	7	2.489362	0.032014	0.401709	0.190476	0.34026
WNT7B	Up_gene	4	2.62766	0.039645	0.380567	0	0.255952
ITGB8	Up_gene	4	2.723404	0.021353	0.367188	0.166667	0.380435
ALPI	Up_gene	3	3.361702	0.025814	0.297468	0	0.333333
AVPR1A	Up_gene	3	3.276596	0.042324	0.305195	0	0.333333
MFSD2A	Up_gene	3	1.666667	0.355556	0.6	0	0.666667
GALNT3	Up_gene	3	1.666667	0.355556	0.6	0	0.666667
SFRP1	Up_gene	2	2.765957	0.036954	0.361538	0	0.5

Up and down represent upregulated expression and downregulated expression, respectively.