Hyperhomocysteinemia Associated with Multiple Organ Failure in Acute Pancreatitis Patients

Table 3

Univariate logistic regression analysis of multiple organ failure in AP patients.

Variable	Regression coefficient B	OR (95% CI)	value
Age	0.010	1.010 (1.002–1.017)	0.10
Male sex	0.158	1.171 (0.944–1.452)	0.151
Hypertension	0.287	1.332 (1.028–1.727)	0.030
Diabetes mellitus	0.016	1.016 (0.752–1.373)	0.916
APACHE II score	0.536	1.709 (1.614–1.809)	<0.001
CCI	0.085	1.089 (0.912–1.136)	0.059
Homocysteine	0.232	1.271 (1.121–1.460)	<0.001
Pancreatic necrosis	5.834	341.682 (210.124–555.607)	<0.001
Surgery accepted	1.211	3.355 (2.498–4.507)	<0.001
ICU admission	5.457	234.424 (114.145–481.442)	<0.001
WBC	0.088	1.092 (1.073–1.113)	<0.001
CRP	0.008	1.008 (1.007–1.009)	<0.001
Etiology (reference to others)
Biliary pancreatitis	0.964	2.622 (1.520–4.526)	0.001
Hypertriglyceridemia	0.739	2.094 (1.210–3.622)	0.008
Alcohol	0.711	2.036 (1.030–4.022)	0.041
HCT	−0.017	0.984 (0.969–0.998)	0.030
BUN	0.128	1.137 (1.107–1.167)	<0.001
Creatinine	0.007	1.007 (1.005–1.008)	<0.001
Glucose	0.081	1.084 (1.057–1.112)	<0.001
TG	0.000	1.000 (0.985–1.014)	0.952
HDL	−1.005	0.366 (0.272–0.493)	<0.001
LDH	0.004	1.004 (1.003–1.004)	<0.001
Myoglobin	0.004	1.004 (1.003–1.005)	<0.001
Creatine kinase	0.001	1.001 (1.001–1.002)	<0.001