lncRNA CASC2 Enhances <sup>131</sup>I Sensitivity in Papillary Thyroid Cancer by Sponging miR-155

<div>Overexpression of CASC2 inhibits <sup>131</sup>I resistance in resistant papillary thyroid cancer cells. (a, b) qRT-PCR was used to measure the expression change of CASC2 in res-TPC-1 and res-IHH-4 cells after transfection of CASC2 overexpression vector or pcDNA. (c, d) Cell viability and (e) apoptosis in res-TPC-1 and res-IHH-4 cells transfected with CASC2 overexpression vector or pcDNA were determined after treatment of the indicated dose of <sup>131</sup>I for 12 h. <span class="nowrap"><svg height="10.7395pt" id="M67" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -10.1025 50.9184 10.7395" width="50.9184pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M486 158C486 177 478 202 466 220C413 228 386 236 336 262C386 288 413 297 466 304C478 323 486 347 485 366C470 376 444 381 422 380C389 338 368 319 321 288C323 345 329 372 349 422C339 442 322 461 305 470C289 461 271 442 262 422C281 372 287 345 290 288C243 319 222 338 189 380C167 381 142 376 125 366C125 347 133 322 145 304C198 296 225 288 275 262C225 236 198 227 145 220C133 201 125 177 126 158C141 148 167 143 189 144C222 186 243 205 290 236C288 179 282 152 262 102C272 82 289 63 306 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BioMed Research International

fig4

Figure 4

Figure 4: lncRNA CASC2 Enhances <sup>131</sup>I Sensitivity in Papillary Thyroid Cancer by Sponging miR-155 

BioMed Research International

lncRNA CASC2 Enhances 131I Sensitivity in Papillary Thyroid Cancer by Sponging miR-155

Figure 4

lncRNA CASC2 Enhances ¹³¹I Sensitivity in Papillary Thyroid Cancer by Sponging miR-155