lncRNA CASC2 Enhances ¹³¹I Sensitivity in Papillary Thyroid Cancer by Sponging miR-155

Figure 6

miR-155 attenuates CASC2-mediated ¹³¹I resistance inhibition in resistant papillary thyroid cancer cells. (a, b) qRT-PCR detected the level of miR-155 in TPC-1, res-TPC-1, IHH-4, and res-IHH-4 cells. (c, d) qRT-PCR was carried out to measure the expression change of miR-155 in res-TPC-1 and res-IHH-4 cells after transfection of pcDNA, CASC2 overexpression vector, CASC2 overexpression vector+miR-NC, or miR-155 mimic. (e, f) Cell viability and (g, h) apoptosis were examined in res-TPC-1 and res-IHH-4 cells transfected with pcDNA, CASC2 overexpression vector, CASC2 overexpression vector+miR-NC, or miR-155 mimic after exposure to the indicated dose of ¹³¹I for 12 h. and .

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