Prognostic Factors Analysis and Nomogram Construction of Dual Primary Lung Cancer: A Population Study

Table 3

The final clinicopathological characteristics of all DPLC patients.

Variables	No. of patients (%)	36-month OS (%)	60-month OS (%)	value
Age				<0.001
<65	1370 (25.3)	47.4	36.3
≥65	4041 (74.7)	38.8	24.7
Gender				<0.001
Female	2894 (53.4)	45.9	32.2
Male	2517 (46.6)	35.4	22.5
Race				<0.001
White	4613 (85.3)	40.3	27.2
Black	528 (9.8)	38.9	24.1
Others	270 (4.9)	55.7	39.5
Histologic type				<0.001
Aden-aden	1000 (18.5)	47.4	34.9
Squa-squa	578 (10.7)	36.7	21.0
Squa-aden	254 (4.6)	33.8	22.0
Aden-squa	224 (4.2)	36.3	21.5
BAC-aden	147 (2.7)	54.8	41.7
Others	3208 (59.3)	40.0	26.8
Interval				<0.001
<6 months	437 (11.5)	48.0	35.2
≥6 months	3354 (88.5)	40.0	26.0
Primary site				0.003
Bilateral	3559 (65.7)	42.0	28.4
Ipsilateral	1852 (34.3)	38.9	26.4
Grade				<0.001
I/well	180 (3.4)	69.0	53.2
II/moderate	894 (16.6)	52.3	39.4
III/poor	1401 (25.8)	44.2	28.6
IV/undifferentiated	254 (4.6)	34.0	19.8
Others/unknown	2682 (49.6)	34.1	22.0
Stage				<0.001
IA	908 (16.7)	61.7	45.7
IB	998 (18.5)	52.9	36.0
IIA	146 (2.6)	43.5	28.7
IIB	298 (5.5)	43.7	29.6
IIIA	681 (12.6)	34.3	22.3
IIIB	992 (18.4)	39.2	25.4
IV	1399 (25.7)	21.9	13.1
LN metastasis				<0.001
No/unknown	2867 (52.9)	52.7	36.8
Yes	2544 (47.1)	27.7	17.3
Surgery				<0.001
Yes-yes	1866 (34.5)	59.6	44.7
Yes-no	2130 (39.4)	31.7	18.3
No-yes	263 (4.8)	49.8	34.4
No-no	1152 (21.3)	24.3	9.6
Radiation				<0.001
Yes-yes	745 (13.8)	33.2	16.9
Yes-no	741 (13.7)	30.1	18.3
No-yes	1390 (25.7)	39.5	24.0
No-no	2535 (46.8)	46.8	34.1
Chemotherapy				<0.001
Yes-yes	740 (13.6)	28.4	17.6
Yes-no	1149 (21.3)	46.1	32.3
No-yes	915 (16.9)	29.8	19.6
No-no	2607 (48.2)	46.1	31.2